High Throughput Determination of VX in Drinking Water by Immunomagnetic Separation and Isotope Dilution High Performance Liquid Chromatography Tandem Mass Spectrometry (HPLC/MS/MS)
Citation:
U.S. EPA. High Throughput Determination of VX in Drinking Water by Immunomagnetic Separation and Isotope Dilution High Performance Liquid Chromatography Tandem Mass Spectrometry (HPLC/MS/MS). U.S. Environmental Protection Agency, Washington, DC, 2013.
Impact/Purpose:
This document provides the standard operating procedure for determination of the chemical warfare agent VX (O-Ethyl S-2-Diisopropylamino-Ethyl Methylphosphonothioate) in drinking water by isotope dilution liquid chromatography tandem mass spectrometer (LC/MS/MS). This method was adapted from one that was initially developed by the Centers for Disease Control and Prevention, in the National Center for Environmental Health for the determination and quantitation of VX in aqueous matrices. This method is designed to support site-specific cleanup goals of environmental remediation activities following a homeland security incident involving this analyte.
Description:
Methods Report